Table 3 Module comparison and evaluation.

From: Identification of Key Components in Colon Adenocarcinoma Using Transcriptome to Interactome Multilayer Framework

 

Module Seed

USF1

YY1

JUN

EGR1

SP1

MXI1

E2F1

1

# module genes

153

140

140

250

239

63

156

2

# COAD genes in 1

94 (61%)

51 (36%)

64 (45%)

116 (46%)

99 (41%)

19 (30%)

39 (25%)

3

# DEGs in 1

21 (13%)

8 (5%)

11 (7%)

40 (16%)

35 (14%)

1 (1%)

130 (83%)

4

# DEGs in (1–2)

3 (5%)

4 (4%)

3 (3%)

12 (8%)

14 (10%)

1 (2%)

100 (85%)

5

# Survival Candidate in 4

1

0

0

0

0

0

9

  1. The first row demonstrates the number of genes inside each module. For each module, its overlap with COAD has been presented in the second row. Values in the third row are the count of DEGs inside each module. However, the fourth row shows the number of DEGs in module genes, which were not previously reported as COAD-related genes in databases. Additionally, the number of genes with significant effects on patients’ survival (according to the fourth row) are presented in the fifth row.
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