Table 4 Significant pathways for the module USF1.

From: Identification of Key Components in Colon Adenocarcinoma Using Transcriptome to Interactome Multilayer Framework

Term

P-value

Adj. P-value

Z-score

Androgen receptor signaling pathway WP138

6.79E-58

2.17E-55

−1.38815

TGF-beta Signaling Pathway WP366

7.66E-38

1.23E-35

−1.2601

Nuclear Receptors WP170

6.06E-31

4.85E-29

−1.53161

Adipogenesis WP236

8.28E-30

5.3E-28

−1.04883

Cell Cycle WP179

1.46E-27

7.77E-26

−1.11229

AGE/RAGE pathway WP2324

2.48E-25

1.13E-23

−1.9584

Non-small cell lung cancer WP4255

1.44E-23

4.62E-22

−1.53125

RAC1/PAK1/p38/MMP2 Pathway WP3303

2.65E-23

7.06E-22

−1.39478

Oncostatin M Signaling Pathway WP2374

5.77E-22

1.35E-20

−1.85675

Circadian rhythm related genes WP3594

5.89E-22

1.35E-20

−0.88343

TGF-beta Receptor Signaling WP560

1.01E-21

2.16E-20

−2.33059

VEGFA-VEGFR2 Signaling Pathway WP3888

1.54E-21

3.09E-20

−0.79477

DNA Damage Response (only ATM dependent) WP710

1.04E-20

1.97E-19

−1.06194

TNF related weak inducer of apoptosis (TWEAK) Signaling Pathway WP2036

5.64E-20

9.49E-19

−2.38891

Brain-Derived Neurotrophic Factor (BDNF) signaling pathway WP2380

8.93E-20

1.43E-18

−0.86385

Chromosomal and microsatellite instability in colorectal cancer WP4216

2.24E-19

3.41E-18

−1.18043

Energy Metabolism WP1541

3.53E-19

5.13E-18

−1.95291

Leptin signaling pathway WP2034

4.51E-19

6.28E-18

−1.01867

IL-4 Signaling Pathway WP395

3.2E-18

4.1E-17

−1.68254

RANKL/RANK (Receptor activator of NFKB (ligand)) Signaling Pathway WP2018

4.26E-18

5.25E-17

−1.67297

ErbB Signaling Pathway WP673

9.84E-18

1.12E-16

−1.27747

Aryl Hydrocarbon Receptor WP2586

1.5E-17

1.65E-16

−1.90374

Thymic Stromal LymphoPoietin (TSLP) Signaling Pathway WP2203

2.06E-17

2.2E-16

−2.11

Wnt/beta-catenin Signaling Pathway in Leukemia WP3658

2.55E-17

2.64E-16

−2.43499

Nuclear Receptors Meta-Pathway WP2882

3.15E-17

3.15E-16

−0.67084

DNA Damage Response WP707

1.11E-16

1.08E-15

−1.09236

miRNA Regulation of DNA Damage Response WP1530

2.12E-16

1.94E-15

−1.33999

Non-genomic actions of 1,25 dihydroxyvitamin D3 WP4341

2.12E-16

1.94E-15

−0.88709

Vitamin D in inflammatory diseases WP4482

3.05E-16

2.71E-15

−2.36581

Corticotropin-releasing hormone signaling pathway WP2355

4.19E-16

3.62E-15

−1.07055

Integrated Cancer Pathway WP1971

4.43E-16

3.64E-15

−2.03412

Interleukin-11 Signaling Pathway WP2332

4.43E-16

3.64E-15

−2.02649

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