Figure 4
From: MiR-4435 is an UQCRB-related circulating miRNA in human colorectal cancer
MiR-4435 is regulated by the UQCRB inhibitor, A1938. (a,b) Effect of A1938 on miR-4435 expression levels in mutant UQCRB-expressing cell lines and colon cancer cells. (c,d) Effect of A1938 on TIMP3 expression levels in mutant UQCRB-expressing cell lines and colon cancer cells. β-actin was used as an internal control. (e,f) Cell proliferation after transfection of miR-4435 inhibitor. (g,h) Effect of A1938 on cell proliferation. Cells were treated with A1938 (30 µM) for 36 h. All quantified data are presented as mean ± S.E.M compared to control (*p < 0.05, **p < 0.01, ***p < 0.0001). These all images are representative of 3 repeated independently repeated experiments.
