Figure 5

A properly functioning molecular clock mechanism is necessary for circadian modulation of light avoidance behavior. Larvae with mutated clock mechanism, per⁰¹ and clk^Jrk are tested for their light avoidance behavior. Both mutants are still able to perform spatial and temporal navigation strategies through processing the corresponding information. However, since the clock mechanism is disrupted, circadian modulation is abolished for both types of navigation strategies. (A,B) per⁰¹ larvae. (A.I–A.III) Spatial navigation strategies. (B.I–B.III.) Temporal navigation strategies. (A’,B’) clk^Jrk larvae. (A’.I–A’.III) Spatial navigation strategies. (B’.I–B’.III) Temporal navigation strategies. Data for each time-point are shown as means and the error bars indicate ± SEM. Circles indicate the means of individual experiments (n = 10). Statistical data can be found as Supplementary Table S4. *p < 0.05, **p < 0.01, ***p < 0.001, NS = not significant. Column statistics significance is indicated on the left side of each graph. All statistical comparisons between time-points are indicated on the right side of each graph.