Table 3 Biochemical assay in serum (Data presented as mean ± SD, n = 6).

From: PEGylated nano-graphene oxide as a nanocarrier for delivering mixed anticancer drugs to improve anticancer activity

Parameters

PBS

pGO

pGO-Pt/DOX

Pt/DOX

ALT (alanine aminotransferase) (U/L)

6.8 ± 6.6

38.6 ± 13.0

39.6 ± 5.9

45.6 ± 11.3

AST (aspartate aminotransferase) (U/L)

147 ± 28

143 ± 26

164.6 ± 23

147 ± 51

ALP (alkaline phosphatase) (U/L)

70.6 ± 9.5

72.2 ± 22.8

74.2 ± 17.3

74.2 ± 19.1

BUN (blood urea nitrogen) (mmol/L)

7.7 ± 1.9

8.8 ± 4.2

9.6 ± 3.8

24.4 ± 8.9*

CK (creatine kinase) (U/L)

452 ± 60

479 ± 70

439 ± 111

627 ± 106*

LDH (lactate dehydrogenase) (U/L)

491 ± 66

498 ± 85

478 ± 118

652 ± 165*

Back to article page