Table 1 Baseline characteristics of enrolled patients and comparison between ACLF group and non-ACLF group.

From: Noninvasive models for predicting poor prognosis of chronic HBV infection patients precipitating acute HEV infection

 

Total (n = 193)

ACLF (n = 67)

Non-ACLF (n = 126)

P value

Age (years)

49 ± 14

54 ± 13

47 ± 14

 < 0.001

Male n (%)

138 (71.5%)

85 (67.5%)

53 (79.1%)

0.088

ALT (IU/L)

375 (85–893)

310 (81–878)

434 (87–901)

<0.001

AST (IU/L)

196 (80–532)

176 (61–443)

249 (93–659)

0.021

GGT (IU/L)

118 (63–182)

94 (53–138)

135 (69–201)

0.015

TB (mg/dl)

5.64 (1.30–15.55)

16.5 (8.20–25.70)

2.19 (0.97–8.97)

<0.001

ALB (g/L)

36 ± 6

33 ± 6

38 ± 6

<0.001

GLB (g/L)

29 (26–35)

30 (24–37)

29 (26–33)

0.558

Cr (mg/dl)

0.73 (0.62–0.82)

0.76 (0.59–0.87)

0.72 (0.62–0.81)

0.312

WBC (109 cells/L)

5.3 (4.0–6.9)

6.1 (4.5–8.4)

5.1 (3.9–6.3)

0.007

PLT (109 cells/L)

127 ± 63

99 ± 54

141 ± 64

<0.001

INR

1.16 (1.02–1.58)

1.85 (1.53–2.44)

1.08 (0.99–1.19)

<0.001

Cirrhosis, n (%)

71 (36.8%)

42 (62.7%)

29 (23.0%)

<0.001

HE, n (%)

37 (19.2%)

34 (50.7%)

3 (2.4%)

<0.001

Ascites, n (%)

66 (34.2%)

49 (73.1%)

17 (13.5%)

<0.001

CTP score

7 (6–10)

11 (11–13)

6 (5–7)

<0.001

MELD score

12 (5–19)

21 (16–27)

7 (3–13)

<0.001

CLIF-C ADs

40 (35–48)

49 (46–59)

37 (34–41)

<0.001

  1. ACLF, acute-on-chronic liver failure; ALT, alanine aminotransferase; AST, aspartate aminotransferase; GGT, gamma-glutamyl transpeptidase; TB, total bilirubin; ALB, albumin; GLB, globulin; Cr, creatinine; WBC, White blood cell count; PLT, Platelet count; INR, international Normalized Ratio; HE, hepatic encephalopathy; CTP score, Child-Turcotte-Pugh score; MELD score, model for end-stage liver disease score; CLIF-C ADs, Chronic Liver Failure Consortium acute decompensation score.
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