Figure 2

Western blot analysis of brain homogenates from mice challenged with brain homogenate from elk with chronic wasting disease. Lanes 1 and 11, markers. All mice express M132 elk prion protein. LL/LM/MM indicates the prion protein genotype of the elk donor for the first passage study i.e. LL132, LM132 and MM132 respectively. P1, first passage (elk to mouse); P2, second passage (mouse to mouse). Anti-prion protein antibody 6H4.