Figure 4 | Scientific Reports

Figure 4

From: Novel Strain of the Chronic Wasting Disease Agent Isolated From Experimentally Inoculated Elk With LL132 Prion Protein

Figure 4

Patterns of PrPSc immunoreactivity in brains from mice from the second passage of CWD-affected elk brain homogenate from LL132 (a), LM132 (b) and MM132 (c) elk. In LL mice (a) immunoreactivity is present as diffuse immunolabeling of the neuropil while in LM (b) and MM (c) mice there are widespread medium to large aggregates in addition to diffuse immunolabeling of the neuropil. PrPSc detected with mAb 6H4.

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