Figure 1 | Scientific Reports

Figure 1

From: PSEN1 variants in Korean patients with clinically suspicious early-onset familial Alzheimer’s disease

Figure 1

Evolutionary conservation of the amino acid residues for LPV (blue) and VUS (red) sites. Multiple sequence alignment shows the amino acid sites of four LPVs and two VUSs, (A) c.356 C > T (p.Thr119Ile), c.358 G > A (p.Glu120Lys) and c.476 A > G (p.Tyr159Cys), (B) c.845 T > C (p.Leu282Pro), (C) c.853 G > T (p.Ala285Ser), (D) c.1165 T > C (p.Tyr389His) and c.1166 A > C (p.Tyr389Ser).

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