Table 1 Genotype and allele frequencies distribution of ADIPOQ SNPs in T2D patients in Gujarat and J&K population.
SNP | N | Genotype | Allele | Odds Ratio [95% CI] (p-value) | |||||
|---|---|---|---|---|---|---|---|---|---|
Allelic | Additive | Dominant | Recessive | ||||||
Gujarat Population | |||||||||
rs266729 | CC | CG + GG | C | G | 1.23 [0.95–1.59] (0.118) | 0.2644 | 1.46 [0.72–2.95] (0.1443) | 1.28 [0.92–1.77] (0.1432) | |
Controls | 286 | 155 | 131 | 427 | 145 | ||||
T2D Patients | 285 | 137 | 148 | 402 | 168 | ||||
rs17846866 | TT | TG + GG | T | G | 2.33 [1.85–2.93] (<0.0001) | <0.0001 | 1.46 [0.15–2.02] (<0.0001) | 1.79 [1.36–2.35] (<0.0001) | |
Controls | 493 | 363 | 130 | 847 | 139 | ||||
T2D Patients | 475 | 289 | 186 | 687 | 236 | ||||
rs2241766 | TT | TG + GG | T | G | 0.86 [0.64–1.18] (0.3722) | 0.6704 | 0.74 [0.22- 2.55] (0.6325) | 0.86 [0.61- 1.21] (0.3954) | |
Controls | 467 | 362 | 105 | 822 | 112 | ||||
T2D Patients | 359 | 287 | 72 | 642 | 76 | ||||
rs1501299 | GG | GT + TT | G | T | 1.72 [1.42–2.09] (<0.0001) | <0.0001 | 1.99 [1.28–3.08] (0.0018) | 2.05 [1.57–2.65] (<0.0001) | |
Controls | 489 | 255 | 216 | 692 | 250 | ||||
T2D Patients | 464 | 172 | 298 | 579 | 361 | ||||
Jammu and Kashmir Population | |||||||||
rs266729 | CC | CG + GG | C | G | 1.34 [1.05–1.69] (0.0168) | 0.0365 | 1.26 [0.67–2.36] (0.2294) | 1.47 [1.09–1.96] (0.0101) | |
Controls | 290 | 151 | 139 | 423 | 157 | ||||
T2D Patients | 503 | 309 | 194 | 787 | 219 | ||||
rs17846866# | TT | TG + GG | T | G | 0.95 [0.70–1.29] (0.3827) | — | — | 0.95 [0.71–1.27] (0.3663) | |
Controls | 300 | 141 | 159 | 206 | 94 | ||||
T2D Patients | 507 | 232 | 275 | 343 | 164 | ||||
rs2241766 | TT | TG + GG | T | G | 0.72 [0.52–1.02] (0.0613) | 0.2041 | 0.646 [0.23–1.83] (0.2039) | 0.71 [0.49–1.04] (0.0788) | |
Controls | 299 | 251 | 48 | 545 | 53 | ||||
T2D Patients | 507 | 400 | 107 | 894 | 120 | ||||
rs1501299 | GG | GT + TT | G | T | 1.09 [0.86–1.40] (0.2248) | 0.7452 | 1.12 [0.59–2.13] (0.3670) | 1.12 [0.83–1.51] (0.2247) | |
Controls | 289 | 170 | 119 | 443 | 135 | ||||
T2D Patients | 502 | 309 | 193 | 786 | 218 | ||||
