Figure 2
Number of proteins in mutually exclusive protein clusters formed due to different combinations of seven proteomes (M. tuberculosis, M. bovis, M. paratuberculosis and non-granuloma forming Yersinia species like Y. pseudotuberculosis, Y. enterocolitica and Y. frederiksenii). Solid dots show presence of proteins in the corresponding proteome and line between two solid dots shows presence of orthologous proteins in the two proteomes. The vertical bars show the number of shared homologous proteins (orthologous proteins) among the proteomes. Single solid dot represents species unique proteins. The plot was drawn from UpSet plot tool (https://gehlenborglab.shinyapps.io/upsetr/). Panel (a–c) Shows combination of proteomes which shared >10, ≤10 and 0 orthologous proteins respectively85. ‘*’ represent proteins shared among all seven proteomes, ‘$’ and ‘#’ shows intra-genus conserved proteins of Mycobacterium spp. and Yersinia spp respectively.
