Figure 1 | Scientific Reports

Figure 1

From: Functional omics analyses reveal only minor effects of microRNAs on human somatic stem cell differentiation

Figure 1

mRNA expression analysis of native and XXL-USSC. (A) Heat map of differentially expressed mRNAs in USSC lines 4/101, 4/146, and 5/03 (p < 0.01, q < 0.05, FC > 1.5) at time points native, 3d, 7d, 14d of XXL-incubation. USSC lines and time points are colour-coded at the top of the heat map. The heat map represents two main clusters of up- and downregulated mRNAs. Top categorical gene ontology enrichment annotations (q < 0.05) based on DAVID database are given for each cluster (top 10 are shown). (B,B’) Venn diagrams of upregulated (B) and downregulated (B’) mRNA at the respective time points of XXL incubation in comparison to native USSC.

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