Figure 2 | Scientific Reports

Figure 2

From: Functional omics analyses reveal only minor effects of microRNAs on human somatic stem cell differentiation

Figure 2

Proteome analysis of native and XXL-USSC. (A) Correlation plots of quantified proteins between native and XXL-treated USSC lines. Pearson’s correlations indicate a high similarity between the biological replicates. (B) Heat map of differentially abundant proteins in USSC lines 4/101, 4/146, 5/03, 5/73, 7/18, and 8/77 (p < 0.01, q < 0.05, FC > 1.5) at time points native, 3d, 7d, of XXL-incubation. USSC lines and time points are colour-coded at the top of the heat map. The heat map represents two main clusters of up- and downregulated proteins. Top categorical gene ontology enrichment annotations (q < 0.05) based on DAVID database are given (top 10 are shown). (C) Differentially abundant proteins at 3d and 7d XXL-USSC compared to native USSC. Black arrows denote the regulatory direction.

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