Table 2 Positions of QTLs associated with trabecular and cortical traits.

From: A genome-wide association study in mice reveals a role for Rhbdf2 in skeletal homeostasis

QTL

Trait

Chr

logP

99th % thresh.

H2r

Simulation

50% CI (Mb)

90% CI (Mb)

95% CI (Mb)

Position

Width

Position

Width

Position

Width

Trl7

BV/TV

11

7.60

4.90

0.69

116.6–116.7

0.12

113.6–118.1

4.50

112.1–118.3

6.40

Trl7

Tb.N

11

6.80

4.84

0.71

116.6–116.87

0.29

114.2–118.35

4.15

112.41–118.68

6.27

Trl8

Tb.Th

4

8.00

4.50

0.61

117.2–117.58.

0.32

113.05–125.54

12.49

110.87–126.52

15.65

Trl9

Tb.Sp

5

9.40

6.01

0.78

105.78–106.14

0.35

101.6–109.11

7.54

99.8–110.39

10.62

Crl1

Ct.Th

4

8.20

4.80

0.80

9.29–9.72

0.43

4.0–11.7

7.70

3.4–11.8

8.49

Crl2

vBMD

3

9.80

4.93

0.86

97.2–97.4

0.20

94.4–103.1

8.50

93.22–104.3

10.80

  1. Chr = chromosome; logP = negative 10-base logarithm of P value; Sig = genome-wide significance level; 99th % threshold logP = threshold used to define cut-off for QTL peaks (Fig. 4); \({{{\rm{H}}}_{{\rm{r}}}}^{2}\) = regional heritability (the proprtion to which the locus explains the phenotypic variability). Positions and widths of the simulation-based 50, 90, and 95% CIs are given.
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