Figure 4

Effect of calcium blockers on adenosine-induced cAMP accumulation in T84 cells. (a) Intracellular cAMP levels in confluent T84 cells incubated with various concentrations of nifedipine, nisoldipine, amlodipine, or nitrendipine. (b) Intracellular cAMP levels in the presence of varying concentrations of adenosine (0–100 μM) or 10 µM BAY60-6583 for 15 min. (c) Intracellular cAMP levels in the presence of 100 µM adenosine (Ado) and various concentrations of nisoldipine, amlodipine, or nitrendipine. All data are expressed as mean ± SEM.