Table 4 Comparison of results from this study versus published results from other similar studies undertaken in other sites in the South of England.
Study result | Site of study | |||
|---|---|---|---|---|
ICHMP cohort | The Royal Marsden (George et al.5) | University College London Hospital (Rahman et al.8) | East Anglia (Plaskocinska et al.11) | |
Number of patients | 255 | 207 | 122 | 232 |
Criteria for testing | Epithelial ovarian cancer | Non-mucinous ovarian cancer | High grade non-mucinous ovarian cancer | Newly-diagnosed epithelial ovarian cancer |
BRCAm, % (n) | ||||
13.33% (34) | 15.94% (33) | 14.75% (18) | 7.76% (18) | |
VUS, % (n) | 0% (0) | 0% (0) | 7.38% (9) | 6.47% (15) |
Age of diagnosis BRCAwt, years (range) | Mean 62.9 (31–91) | Mean 57.8 (22–81) | Median 62 (28–88) | Mean 66.1 (28–89) |
Age of diagnosis BRCAm, years (range) | Mean 57.8 (39–78) | Mean 53.9 (30–87) | Median 58 (42–74) | Mean 49.5 (40–75) |
Turnaround time of testing service | Mean 20.6 calendar days (range 11–42) | Not stated | Median 26 working days (range 14–48) | Median 46 calendar days (range 15–177) |