Table 4 Comparison of results from this study versus published results from other similar studies undertaken in other sites in the South of England.

From: Oncologist-led BRCA ‘mainstreaming’ in the ovarian cancer clinic: A study of 255 patients and its impact on their management

Study result

Site of study

ICHMP cohort

The Royal Marsden (George et al.5)

University College London Hospital (Rahman et al.8)

East Anglia (Plaskocinska et al.11)

Number of patients

255

207

122

232

Criteria for testing

Epithelial ovarian cancer

Non-mucinous ovarian cancer

High grade non-mucinous ovarian cancer

Newly-diagnosed epithelial ovarian cancer

BRCAm, % (n)

    
 

13.33% (34)

15.94% (33)

14.75% (18)

7.76% (18)

VUS, % (n)

0% (0)

0% (0)

7.38% (9)

6.47% (15)

Age of diagnosis BRCAwt, years (range)

Mean 62.9 (31–91)

Mean 57.8 (22–81)

Median 62 (28–88)

Mean 66.1 (28–89)

Age of diagnosis BRCAm, years (range)

Mean 57.8 (39–78)

Mean 53.9 (30–87)

Median 58 (42–74)

Mean 49.5 (40–75)

Turnaround time of testing service

Mean 20.6 calendar days (range 11–42)

Not stated

Median 26 working days (range 14–48)

Median 46 calendar days (range 15–177)