Figure 1 | Scientific Reports

Figure 1

From: Initial interaction of citrate-coated iron oxide nanoparticles with the glycocalyx of THP-1 monocytes assessed by real-time magnetic particle spectroscopy and electron microscopy

Figure 1

MPS measurements at \(\hat{B}\) = 25 mT of VSOP in liquid suspension. MPS signals were acquired over a dilution range of the VSOP samples from 65 µg(Fe) down to 3 ng(Fe) iron. The uncertainty bars indicate the intrinsic noise of the MPS device determined by empty sample holder measurements (n = 100). The upper graph shows the ratio of the third A3 to the fifth A5 harmonic amplitude representing the concentration independent slope of the MPS spectrum (grey circles) showing a mean A5/A3 ratio of 6.05% (solid line). The lower graph displays that the signal amplitudes A3 (red triangles) and A5 (blue squares) are decreasing linearly with sample iron content. The limit of detection (LOD) of the respective harmonic amplitude results from 20 repeated measurements of an empty sample holder (dashed lines).

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