Table 1 Ten most upregulated URs ranked by z-score. p-value as well as the number of DEGs contributing to the URs are displayed. DSS, dextran sulfate sodium; CS Low, 450 μg/L TPM from CS; CS Med, 600 μg/L TPM from CS; CS High, 750 μg/L TPM from CS.

From: The reduction of DSS-induced colitis severity in mice exposed to cigarette smoke is linked to immune modulation and microbial shifts

Top 10 UR

p-value

Sham + DSS

CS Low + DSS

CS Med + DSS

CS High + DSS

Number of differentially expressed genes

INFγ

2.03E-25

69

18

3

0

IRF7

2.12E-24

36

7

0

0

INFα

1.35E-21

38

6

0

0

Stat1

4.23E-34

46

8

1

0

TNF

2.62E-07

47

13

1

0

IFNB1

1.70E-19

30

5

0

0

TLR9

1.14E-12

21

7

0

0

TLR3

1.15E-13

23

5

0

0

IFNAR1

1.19E-21

25

6

0

0

SMARCA4

5.19E-04

18

6

0

0