Figure 4
From: Ramped pulse shapes are more efficient for cochlear implant stimulation in an animal model

RampUP is more charge-efficient than Rec at longer phase durations. Thresholds of increasing phase durations (25 µs, 50 µs, 75 µs) with Rec (black) and rampUP (green) in terms of (a) amplitude current level and (b) charge injected. Solid line, anodic-first pulses; dashed, cathodic-first pulses. n = 12 mice for 25 µs/phase and 50 µs/phase, n = 9 mice for 75 µs/phase. Black and green asterisks denote significant effect in post hoc test of the pulse shape*polarity interaction (Tukey HSD) of Rec and rampUP, respectively. *p ≤ 0.05. Only one error bar is shown for simplicity. (c) Latency of wave II at three dB (re 1 nC) above threshold for ramp Rec (black) and rampUP (green). Each circle is data from one mouse. M7 and M9 are excluded. Closed circles, anodic-first pulses; open circles, cathodic-first pulses. n = 10 mice for 25 µs/phase, n = 7–8 mice for 50 µs/phase, n = 5–6 mice for 75 µs/phase.