Figure 1 | Scientific Reports

Figure 1

From: Whole embryo culture, transcriptomics and RNA interference identify TBX1 and FGF11 as novel regulators of limb development in the mouse

Figure 1

Cultured E10.5 mouse embryos exhibit evidence of a developmental delay. (A) Quantification of the total somite number in uncultured E10.5 and E11.5 mouse embryos and in ex utero developing E10.5 mouse embryos during 24 hours. (B) Pictures of the right forelimb of uncultured, 24 h ex utero cultured E10.5 and uncultured E11.5 mouse embryos. (C) Assessment of body size corresponding to the Crown to Rump length (hatched white line traced in panel B), head size in µm and the relative limb size (forelimb and hindlimb) of ex utero and in utero developing embryos. The relative sizes of the forelimb and hindlimb correspond to their respective surface normalized by the body size of the embryo. Error bars indicate standard error of the mean ( ± SEM).

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