Figure 5
From: Development of a two-stage limb ischemia model to better simulate human peripheral artery disease
Exercise training led to increased ambulatory ability of mice undergoing 2-stage HLI. (A) Schematic representation of the design of the experiment. (B) Examples of Laser Doppler perfusion imaging (LDPI) images showing the relative perfusion of the limbs of mice in the control (C) and exercise groups (E). (C) Quantitative graph showing no significant difference in the perfusion of the hind limbs of mice after exercise training in comparison to controls. Data analysed by linear mixed effect analysis. (D) The average distance travelled on the treadmill was significantly greater in mice receiving exercise training than sedentary controls. Data analysed by repeated measures 2-way ANOVA.
