Table 2 Mean percent WT ribonuclease activity of ALS associated ANG variants.

From: Loss of angiogenin function is related to earlier ALS onset and a paradoxical increase in ALS duration

ANG Variant

% Mean Ribonuclease Activity

Reference

Q12L

3.4

11,35

K17I

13.1

11,35

K17E

19.0

11,35

R31K

80.1

11,35

C39W

4.2

11,35

K40I

0.9

35

I46V

9.7

11,35

K54E

80.3

11,35

T80S

78.7

12

F100I

39.1

12

V103I

54.1

12

V113I

75

35

H114R

1.6

12

R121H

155.5

35

R121C*

131.2

12

  1. *Concomitant G93D SOD1 mutation.
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