Table 3 Stability of ALS associated ANG variants.

From: Loss of angiogenin function is related to earlier ALS onset and a paradoxical increase in ALS duration

ANG mutation

∆∆G (kcal/mol)

Reference

Q12L

−0.25

11

K17I

−0.48

11

K17E

0.15

11

R31K

−0.48

11

C39W

−5.19

11

K40I

−1.27

11

I46V

−1.50

11