Table 2 Effect of HFD on KOR and Pdyn expression in the brain. Regions indicated with bold show expression above the detection level. - indicates no expression, + marginal expression and +++ significant expression.

From: Modulation of feeding behavior and metabolism by dynorphin

Brain region

Position (Bregma, mm)

KOR

Pdyn

PreL, MO, VO, LO, Pir

2.68–1.98

AID, AIV, PreL, Cg

2.34–1.10

+

AcbSh, AcbC, PreL, IL, Cg, Pir

1.94–1.10

VP, Tu

1.94–0.38

+++

BLA, CeA, Ast, PVN

−0.94–1.82

+++

DG, CA1, LHA, Arc

−1.22–1.82

  1. PreL- prelimbic cortex; MO- medial orbitofrontal cortex; VO- ventral orbitofrontal cortex; LO- lateral orbitofrontal cortex; Pir- piriform cortex; AID- agranular insular cortex, dorsal; AIV- agranular insular cortex, ventral; PreL- prelimbic cortex; Cg- cingulate cortex; AcbSh- accumbens nucleus, shell; AcbC- accumbens nucleus, core; IL- infralimbic cortex; VP- ventral pallidum; Tu- olfactory tubercle; BLA- basolateral amygdaloid nucleus, lateral part; CeA- central amygdaloid nucleus; Ast- amygdalostriatal transition area; PVN- paraventricular hypothalamic nucleus; DG- dentate gyrus; CA1, CA3 –field CA1, CA3 of the hippocampus; LHA- lateral hypothalamic area; Arc- arcuate hypothalamic nucleus.