Figure 2 | Scientific Reports

Figure 2

From: Primary functional brain connections associated with melancholic major depressive disorder and modulation by antidepressants

Figure 2The alt text for this image may have been generated using AI.

The identified 10 functional connections for the melancholic MDD biomarker. (a) Brain regions included in the identified functional connections (FCs) of the melancholic MDD classifier. Cumulative absolute weight of 32 FCs in total, which were selected at least once throughout the LOOCV. The identified 10 FCs are shown in red, and the rest of 22 FCs are in Gray. (c) Distribution of each subject’s weighted linear sum (WLS) was colored by site, in order to check for any potential scanner or site related effect (melancholic MDD: n = 65, HC: n = 65).

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