Table 3 Prognostic factors of overall survival and progression-free survival based upon univariate analysis presented as hazard ratios with 95% confidence intervals.
Variable | Overall survival | |
|---|---|---|
HR (95% CI) | p | |
Rituximab (yes vs no) | 1.51 (0.7–3.2) | 0.28 |
Sex (male vs female) | 1.1 (0.7–1.8) | 0.66 |
Lymphoma stage I, II vs III, IV | 3.1 (1.5–6.4) | 0.003 |
Age (as a categorical value) (>50 and ≤60) vs <50 >60 vs <50 | 1.2 (0.6–2.3) 2.1 (1.2–3.6) | 0.57 0.01 |
IPI 1–2 vs 3–5 | 2.5 (1.4–4.3) | 0.001 |
Type 2 diabetes mellitus | 1.9 (1.2–3.2) | 0.01 |
Pre-existing HF | 2.5 (1.4–4.4) | 0.002 |
Hypertension | 1 (0.6–1.6) | 0.95 |
Lipid abnormalities | 0.8 (0.4–1.6) | 0.44 |
Obesity | 0.9 (0.5–1.6) | 0.76 |
Smoking | 1.1 (0.6–1.9) | 0.69 |
Progression-free survival | ||
Rituximab (yes vs no) | 0.85 (0.5–1.4) | 0.53 |
Sex (male vs female) | 1.25 (0.9–1.8) | 0.23 |
Lymphoma stage I, II vs III, IV | 2.5 (1.5–4.3) | <0.001 |
Age (as a categorical value) (>50 and ≤60) vs <50 >60 vs <50 | 1.0 (0.6–1.6) 1.3 (0.9–2.0) | 1.0 0.16 |
IPI 1–2 vs 3–5 | 2.7 (1.8–4.1) | <0.001 |
Type 2 diabetes mellitus | 1.6 (1.03–2.4) | 0.036 |
Pre-existing HF | 1.9 (1.1–3.1) | 0.014 |
Hypertension | 1.0 (0.7–1.5) | 0.83 |
Lipid abnormalities | 0.9 (0.5–1.7) | 0.77 |
Obesity | 0.8 (0.5–1.3) | 0.43 |
Smoking | 1.3 (0.8–1.9) | 0.28 |