Figure 2 | Scientific Reports

Figure 2

From: Suppression of antibiotic resistance evolution by single-gene deletion

Figure 2

The relationship between IC50 values before and after laboratory evolution. Each dot represents the mean IC50 of 173 deletion strains over 8 replica culture series for (a) CFIX, (b) CPFX, and (c) CP. The average IC50 of the wild-type strain BW25113 (without deletion) for each drug is also presented as the yellow square. Names of some representative genes whose deletion strains show large deviations from the BW25113 control are presented proximal to the corresponding data points. The dotted line shows the function y = x for reference.

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