Figure 3
From: Genome sequencing of human in vitro fertilisation embryos for pathogenic variation screening
Copy number variant charts for an embryo genome sequencing sample from chromosomes 1–22: (A) Target mean depth, where the top intensity bar is the paternal depth, the central bar is the maternal depth and the lower bar is the embryo depth (black indicates no coverage and yellow indicates high coverage); (B) loss of heterozygosity proportion of the variants in the expected state of variant heterozygosity loss for the embryo (green dots); (C) ratio of coverage regions for the embryo sample (blue connector); (D) ratio of binned regions in 10 kb windows (red connector). (E) z-scores of the parents and embryo samples, where the top intensity bar is the paternal depth, the central bar is the maternal depth and the lower bar is the embryo depth (light purple indicates a low a-score dark purple indicates a high z-score).
