Figure 1

Stratification of patients with HNSCC in the TCGA cohort with EMT signature. (A) Patients in the TCGA cohort were clustered by two-way hierarchical clustering using the Pearson correlation distance between genes (rows), Euclidean distance between EMT signature genes (columns), and Ward’s linkage rule. The TCGA cohort was divided into two distinct subgroups of HNSCC: the Mes group (red) and Epi group (blue). The 82 EMT signature genes were separated into distinct epithelial-related genes (green bar) and mesenchymal-related genes (red bar). (B) Kaplan-Meier plots of DFS of patients with HNSCC in the TCGA cohort.