Figure 2

Cross-linking of microCT and histological images in peri-implant (panels a-d) and peri-dental (panels e-h) representative sites of the retrieved samples. (a–d) Peri-implant bone site: (a) MicroCT 3D reconstruction. The titanium implant was previously removed (with a method preventing the bone/implant interface damaging) to achieve the correct X-ray transmission through the sample during the SR-microCT acquisition; (b) MicroCT 2D longitudinal section. Inhomogeneity in mineralization degree and bone ultrastructure throughout the sample was clearly shown. Bar: 300 µm; (c) MicroCT 2D transversal section. Bar: 180 µm; (d) Histologic 2D transversal section. Original magnification: 40×. Bar: 100 µm (e–h) Peri-dental bone site: (e) MicroCT 3D reconstruction; (f) MicroCT 2D longitudinal section: tooth residual with peri-dental bone behind it. Like in peri-implant sites, evidences of Inhomogeneity in mineralization degree and bone ultrastructure were shown. Bar: 300 µm; (g) MicroCT 2D transversal section. Bar: 250 µm; (h) Histologic 2D transversal section. Original magnification: 100×. Bar: 50 µm (T): tooth residual; (I) Implant site, after the implant removing.