Figure 6
From: Longitudinal DNA methylation differences precede type 1 diabetes
Differentially methylated positions included only on the EPIC platform (EPIC-extension DMPs) longitudinally associated with development of T1D. Volcano plot of results from 215,381 probes that passed pre-processing criteria but were only included on the newer EPIC platform. Delta Beta is the longitudinal average methylation difference between T1D cases compared to controls. Candidate probes with adjusted p-value < 0.1 (solid orange circles) were considered EPIC-extension DMPs and annotated to the gene nearest the probe from Ensembl.
