Table 1 Summary table of cell population (mean % ± SD) in early and late apoptosis when treated with three batches of free drugs, liposomes and immunoliposomes for 12 and 72 hoursa.

From: Prototyping Trastuzumab Docetaxel Immunoliposomes with a New FCM-Based Method to Quantify Optimal Antibody Density on Nanoparticles

 

Early apoptosis 12 H

Early apoptosis 72 H

Late apoptosis 12 H

Late apoptosis 72 H

Free drugs 1

14.2 ± 12.7

14.8 ± 9.3

30.5 ± 5.5

52.1 ±10.1

Liposomes 1

10.8 ± 11.5

20.6 ± 14.7

18.6 ± 8.2

40.3 ± 10.0

Immunoliposome 1

12.5 ± 12.7

10.6 ± 2.8

18.8 ± 6.5

42.0 ± 4.3

Free drugs 2

13.6 ± 15.4

11.7 ± 7.1

19.7 ± 1.3

58.9 ± 3.6

Liposomes 2

11.6 ± 9.4

13.1 ± 10.0

17.4 ± 3.4

38.7 ± 5.0

Immunoliposome 2

11.2 ± 9.2

16.6 ± 13.5

27.9 ± 7.2

31.1 ± 9.7

Free drugs 3

9.7 ± 10.5

24.1 ± 12.2

17.8 ± 2.3

37.7 ± 2.8

Liposomes 3

9.3 ± 9.7

11.7 ± 8.1

19.6 ± 5. 1

53.1 ± 8.1

Immunoliposome 3

10.5 ± 14.2

19.8 ± 10.6

20.3 ± 0.8

39.9 ± 2.6

  1. aValues are mean of three or more experiments.