Table 3 Literature reports of preoperative radiotherapy.

From: Preoperative Stereotactic Body Radiotherapy to Portal Vein Tumour Thrombus in Hepatocellular Carcinoma: Clinical and Pathological Analysis

Author

N

Necrosis

Preoperative Treatment

Period from RT to surgery

RR

Acute AEs*

RILD

Wada16

2

60–100%

3D-CRT 60 Gy / 6 fr. and 39 Gy / 13 fr.

3–4 weeks

NA

0%

0%

Kamiyama17

15

Viable-100%

3D-CRT 30–36 Gy / 10–12 fr.

2 weeks

NA

6.7%

0%

Choi24

16

30–100%

TACE + 3D-CRT 30–68 Gy

4.7 months

NA

NA

NA

Yeh23

12

NA

IMRT 60 Gy / 30 fr.

1.2–5 months

11.3%

0%

NA

This study

6

30–100%

SBRT (for PVTT only) 48 Gy / 4 fr.

2 weeks (6-17 days)

75%

0%

0%

  1. Abbreviations: RR: resection rate; HR: hepatic resection NA: not assessed; RILD: radiation-induced liver disease; SBRT: stereotactic body radiotherapy; IMRT: intensity-modulated radiotherapy; TACE: transarterial chemoembolization; 3D-CRT: three-dimensional conformal radiotherapy; RT: radiotherapy;
  2. *worse than grade 2.
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