Table 1 Relationship between frozen-thawed sperm DFI and pup birth rates of embryos derived by IVF or ICSI using frozen-thawed sperm.
From: DNA fragmentation index (DFI) as a measure of sperm quality and fertility in mice
Sperm Count (×106) | Total Motility (%) | Prog. Motility (%) | Normal Heads (%) | Normal Tails (%) | Sperm DFI (%) | 2-cell Rate (%) | Embryos transferred | Pup Rate (%) | |
|---|---|---|---|---|---|---|---|---|---|
IVF no pups (n = 5) | 20.3 ± 10.2 | 45.2 ± 9.3 | 19.0 ± 6.2 | 70.6 ± 17.4 | 68.8 ± 11.2 | 62.7 ± 7.2* | 14.4 ± 9.4# | 206 | 0& |
IVF Ctrl (n = 7) | 19.8 ± 3.8 | 54.4 ± 16.4 | 29.7 ± 12.0 | 74.7 ± 8.4 | 78.9 ± 3.8 | 20.4 ± 7.9* | 32.7 ± 4.9# | 380 | 36.4 ± 12.2& |
ICSI no pups (n = 5) | 7.9 ± 3.0§ | 29.6 ± 24.2 | 3.6 ± 1.9@ | 31.2 ± 16.6Δ | 50.2 ± 31.7 | 73.3 ± 8.1& | 79.6 ± 11.4 | 188 | 0® |
ICSI Ctrl (n = 6) | 22.5 ± 7.2§ | 42.2 ± 12.3 | 21.2 ± 9.1@ | 73.2 ± 6.9Δ | 71.0 ± 6.6 | 28.1 ± 10.7& | 85.8 ± 5.9 | 240 | 23.4 ± 6.0® |