Figure 3

(a) In-vitro drug release studies showing cumulative percentage drug release from CMCS during single drug encapsulation and dual drug encapsulation in PBS (pH-5) for a time period of 72 h at room temperature, (b) Plot of % cell vialbility (in vitro) vs sample concentration for single and dual drug encapsulated CMCS with inverted microscope images at IC50 concentration as inset, (c) Inverted microscope images showing cell viability on addition of 100 µg/ml of drug loaded samples and (d) Microscopy images showing AO-PI staining of MCF-7 cells after treatment with 5-FU + DOX@CMCS with a scale bar of 50 µm. Values are expressed as Mean ± S.D. of 3 independent experiments.