Table 4 Factors associated with the risk of MCI among 660 participants after multiple imputation.

From: Incidence of and Risk factors for Mild Cognitive Impairment in Chinese Older Adults with Multimorbidity in Hong Kong

Variable

Crude HR (95% CI)

P Value

Multivariable-Adjusted HR (95% CI)

P Value

Age

    

  60–69

1 (Reference)

NA

1 (Reference)

NA

  70–79

4.00 (2.04, 7.83)

< 0.001

2.99 (1.21, 7.36)

0.017

  80+

4.72 (1.88, 11.87)

0.001

2.31 (0.75, 7.13)

0.145

Education

    

  > 6y

1 (Reference)

NA

1 (Reference)

NA

  < = 6y

2.28 (1.24, 4.18)

0.007

1.69 (0.89, 3.20)

0.110

Marriage

    

  Married

1 (Reference)

NA

1 (Reference)

NA

  Single/divorced/separated/widowed

2.81 (1.56, 5.04)

0.001

2.06 (1.10, 3.88)

0.025

Social assistance

    

  No

1 (Reference)

NA

1 (Reference)

NA

  Yes

3.05 (1.57, 5.91)

0.001

1.06 (0.43, 2.59)

0.905

Social media use

    

  No

1 (Reference)

NA

1 (Reference)

NA

  Yes

0.40 (0.22, 0.73)

0.003

0.71 (0.37, 1.39)

0.318

Frailty

    

  No frailty

1 (Reference)

NA

1 (Reference)

NA

  Pre-frailty

1.10 (0.57, 2.12)

0.784

1.11 (0.56, 2.22)

0.759

  Frailty

2.19 (0.96, 4.98)

0.061

1.21 (0.47, 3.09)

0.690

Incontinence

    

  No

1 (Reference)

NA

1 (Reference)

NA

  Yes

2.02 (1.09, 3.76)

0.026

1.32 (0.68, 2.59)

0.412

Regular medication use

    

  < 5

1 (Reference)

NA

1 (Reference)

NA

  > = 5

1.85 (1.02, 3.35)

0.044

0.89 (0.39, 2.00)

0.755

Antidiabetics use

    

  No

1 (Reference)

NA

1 (Reference)

NA

  Yes

1.81 (0.99, 3.30)

0.054

1.76 (0.85, 3.64)

0.125

Analgesics use

    

  No

1 (Reference)

NA

1 (Reference)

NA

  Yes

1.93 (0.93, 4.00)

0.078

1.61 (0.68, 3.85)

0.280

  1. CI: confidence interval; HR: hazard ratio; MCI: mild cognitive impairment; NA: not available.