Figure 6
Effects of HIF1A knockdown on the expression of steroidogenic genes and steroidogenesis. Suppression of HIF1 expression by knockdown altered STAR (a), HSD3B (b) and CYP19A1 (c) transcript abundance. (d,e) show the estradiol and progesterone concentrations in the spent culture media. Data were presented in Mean ± SEM values of three independent cell culture experiments (n = 3). Significant differences were acknowledged at the minimum level of p < 0.05 by t-test.
