Figure 7
Effects of HIF1A knockdown on cell proliferation. (a,b) depicts CCND2 and PCNA mRNA expressions upon HIF1A knockdown in granulosa cells under normoxic and hypoxic conditions. (c,d) depict the percent of replicating cells (S-phase) under normoxic and hypoxic conditions, respectively, upon treating with control and HIF1A gapmers. Data were represented in the mean ± SEM values of three independent culture experiments (n = 3). Significant differences were acknowledged at the minimum level of p < 0.05 by t-test.
