Figure 6
From: Development and Characterization of a Benchtop Corneal Puncture Injury Model
Characterization of various CP injury sizes created using benchtop model. (A) Maximum IOP recorded by catheter pressure transducer for different CP object sizes and shapes (n = 3 biological replicates for each). (B) Maximum IOP vs. object diameter correlation plot and resulting linear regression. Dotted lines represents 95% confidence intervals for the regression analysis, and the coefficient of determination (R2) is shown. Triplicate data points are shown for each object diameter tested. (C) OCT volume projection image of the anterior corneal surface for a control eye (left) or after CP injury with 4.2 mm diameter object (right). (D) Surface area (mm2) of the CP injury from volume projections for different CP injury sizes. (n = 3 biological replicates). (E) Sagittal or cross-sectional view for a control eye (left) or after CP injury with 4.2 mm object diameter (right). (F) Approximate diameter (mm) of the CP injury through the corneal stroma for different CP injury sizes (n = 3 biological replicates). Scale bars denote 1 mm. Error bars denote standard deviation.
