Figure 1

The association between the administration of MSE and the levels of total APN and HMW APN and the HMW/total APN ratio in healthy volunteers. The comparison of changes in the levels of total APN (A) and HMW APN (B) and the ratio of HMW/total APN (C) before and on day 14 after the administration of test tablets among the groups of placebo, MSE 150 mg/day and MSE 300 mg/day. P values were calculated by an ANCOVA (*P < 0.05). The bars and error bars represent the unstandardized partial regression coefficients (B values) and SEs, respectively. B values (SEs) and P values were adjusted by the BMI and glycoalbumin plus level of total APN (A) or HMW APN (B) or ratio of HMW/total APN (C) at the baseline. MSE, melinjo seed extract; HMW, high-molecular-weight; APN, adiponectin; DsbA-L, disulfide bond A oxidoreductase-like protein; SE, standard error.