Table 1 Top 15 gene ontology (GO) terms for genes whose upregulation by NMDA was attenuated in KUS-treated retinal ganglion cells.

From: Effect of VCP modulators on gene expression profiles of retinal ganglion cells in an acute injury mouse model

ID

p value

Over-representation

Description

Genes

GO:0051252

0.000903

3.1

regulation of RNA metabolic process

Camta1,Cir1,Csrnp2,Fos,Fosb,Gatad2a,Nr4a1,Rfc1

GO:0010556

0.001284

2.9

regulation of macromolecule biosynthetic process

Camta1,Cir1,Csrnp2,Fos,Fosb,Gatad2a,Nr4a1,Rfc1

GO:0019219

0.001308

2.9

regulation of nucleobase-containing compound metabolic process

Camta1,Cir1,Csrnp2,Fos,Fosb,Gatad2a,Nr4a1,Rfc1

GO:0051171

0.001308

2.9

regulation of nitrogen compound metabolic process

Camta1,Cir1,Csrnp2,Fos,Fosb,Gatad2a,Nr4a1,Rfc1

GO:0031326

0.001326

2.9

regulation of cellular biosynthetic process

Camta1,Cir1,Csrnp2,Fos,Fosb,Gatad2a,Nr4a1,Rfc1

GO:0009889

0.001332

2.9

regulation of biosynthetic process

Camta1,Cir1,Csrnp2,Fos,Fosb,Gatad2a,Nr4a1,Rfc1

GO:0010468

0.00219

2.7

regulation of gene expression

Camta1,Cir1,Csrnp2,Fos,Fosb,Gatad2a,Nr4a1,Rfc1

GO:0060255

0.002518

2.7

regulation of macromolecule metabolic process

Camta1,Cir1,Csrnp2,Fos,Fosb,Gatad2a,Nr4a1,Rfc1

GO:0080090

0.003192

2.6

regulation of primary metabolic process

Camta1,Cir1,Csrnp2,Fos,Fosb,Gatad2a,Nr4a1,Rfc1

GO:0031323

0.003291

2.6

regulation of cellular metabolic process

Camta1,Cir1,Csrnp2,Fos,Fosb,Gatad2a,Nr4a1,Rfc1

GO:0034645

0.001295

2.6

cellular macromolecule biosynthetic process

Camta1,Cir1,Csrnp2,Eif2s3y,Extl1,Fos,Fosb,Gatad2a,Nr4a1,Rfc1

GO:0009059

0.001314

2.6

macromolecule biosynthetic process

Camta1,Cir1,Csrnp2,Eif2s3y,Extl1,Fos,Fosb,Gatad2a,Nr4a1,Rfc1

GO:0019222

0.003592

2.5

regulation of metabolic process

Camta1,Cir1,Csrnp2,Fos,Fosb,Gatad2a,Nr4a1,Rfc1

GO:0034654

0.006007

2.3

nucleobase-containing compound biosynthetic process

Camta1,Cir1,Csrnp2,Fos,Fosb,Gatad2a,Nr4a1,Rfc1

GO:0019438

0.006642

2.3

aromatic compound biosynthetic process

Camta1,Cir1,Csrnp2,Fos,Fosb,Gatad2a,Nr4a1,Rfc1