Figure 4 | Scientific Reports

Figure 4

From: Identification of a novel gene signature for the prediction of recurrence in HCC patients by machine learning of genome-wide databases

Figure 4

The whole study flow. (A) Kaplan-Meier survival analysis and log-rank test were used to screen DFS-related mutant genes from TCGA database and AMC database. Then these genes were cross-verified in TCGA and AMC, and four DFS-related mutant genes were screened out in these two databases; (B) Boruta algorithm, Fisher’s test and Pearson’s test were used to screen race (Asian/non-Asian)-associated mutations from TCGA database; (C) Boruta algorithm, Fisher’s test and Pearson’s test were used to screen vascular invasion-associated mutations from TCGA, AMC and Inserm database; (D) The HCC data in TCGA were used to construct a model for predicting recurrence, and then AMC and 10 HCC patients in our center were used for verification.

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