Figure 6
From: Adaptations of Interferon Regulatory Factor 3 with Transition from Terrestrial to Aquatic Life
Evolution of the vertebrate IRF3 proteins. The evolution of the two conserved motifs in vertebrate IRF3 proteins is illustrated. The major evolutionary events (duplication, loss, and D → N substitution) are shown in yellow background. The vertebrate lineages that have mainly NPHK in the motif A of IRF3 are shown with solid or dashed blue lines. All animal silhouettes were taken and used without modification from http://www.phylopic.org. Images for sharks, coelacanth, and crocodilians are available under the Public Domain Mark 1.0 license. Images for ray-finned fish, amphibians, birds, marsupials, placental mammals, and cetaceans are available under the Public Domain Dedication 1.0 license. The image of the platypus by Sarah Werning is available under the Creative Commons Attribution 3.0 Unported license (https://creativecommons.org/licenses/by/3.0/).
