Table 1 Distribution means of stretched and relaxed chain ensembles of the original neck linker, the Ala-only peptide and 3 modified (mutant-like) structures, with the stretching force value set to 1300 kJ * mol−1 * nm−1. ΔG values equivalent to crossing points between Gaussian curves of stretched and relaxed ensembles.
From: Delineating elastic properties of kinesin linker and their sensitivity to point mutations
Peptide type | < W > stretch [kBT] | < W > relax [kBT] | Δ G [kBT] |
|---|---|---|---|
neck linker | 1569.9 ± 24.9 | 1211.6 ± 68.2 | 1462.4 ± 0.1 |
Ala-only | 949.7 ± 23.9 | 696.0 ± 81.5 | 882 ± 0.1 |
no-Asparagine | 733.7 ± 30.5 | 651.0 ± 63.3 | 690.5 ± 0.1 |
no-Lysine | 985.6 ± 40.4 | 388.0 ± 66.7 | 752.8 ± 0.1 |
no-Proline | 1056.8 ± 26.8 | 888.0 ± 63.9 | 997.6 ± 0.1 |