Table 1 Distribution means of stretched and relaxed chain ensembles of the original neck linker, the Ala-only peptide and 3 modified (mutant-like) structures, with the stretching force value set to 1300 kJ * mol−1 * nm−1. ΔG values equivalent to crossing points between Gaussian curves of stretched and relaxed ensembles.

From: Delineating elastic properties of kinesin linker and their sensitivity to point mutations

Peptide type

 < W > stretch [kBT]

 < W > relax [kBT]

Δ G [kBT]

neck linker

1569.9 ± 24.9

1211.6 ± 68.2

1462.4 ± 0.1

Ala-only

949.7 ± 23.9

696.0 ± 81.5

882 ± 0.1

no-Asparagine

733.7 ± 30.5

651.0 ± 63.3

690.5 ± 0.1

no-Lysine

985.6 ± 40.4

388.0 ± 66.7

752.8 ± 0.1

no-Proline

1056.8 ± 26.8

888.0 ± 63.9

997.6 ± 0.1