Table 1 Baseline variables and Sepsis screen.
From: Neutrophil Volume, conductivity and scatter (VCS) as a screening tool in neonatal sepsis
Sepsis group | Controls | P value | |||
|---|---|---|---|---|---|
Total (n = 304) | Culture positive Sepsis (n = 84) | Probable sepsis (n = 60) | No sepsis (n = 160) | ||
Age (days) # | 4.5 (2–10) | 7 (4–13) | 7.5 (3–14) | 3 (2–5.75) | <0.01 |
Weight (Kg) # | 2.5 (1.96–2.8) | 2.420 (1.78–2.7) | 2.5 (2–2.86) | 2.57 (2.1–2.8) | 0.25 |
Gestation (weeks) # | 38 (36–39) | 37 (36–38) | 37 (36–39) | 38 (37–39) | 0.06 |
Male * | 155 (51) | 44 (52) | 23 (38) | 88 | 0.08 |
Prematurity* | 79 (26) | 29 (34) | 17 (28) | 33 | 0.08 |
Anemia (Hb < 10 g/dl) * | 18 (6) | 15 (18) | 2 (3) | 1 | <0.01 |
Hemoglobin (g/dl) # | 13.9 (12.2–16) | 12.5 (10.8–14.5) | 13.9 (12.8–16.1) | 14.5 (13.20–16.87) | <0.01 |
Total leukocyte count (cu/mm3)# | 10500 (7625–15650) | 11650 (3762.50–17575) | 16200 (11600–18690) | 9800 (8400–11300) | 0.81 |
Absolute neutrophil count (cu/mm3) # | 5800 (3812–10987) | 7400 (1870–13252) | 11935 (8070–14200) | 5090 (4025–6222) | 0.20 |
I/T ratio # | 1 (1–2) | 2 (2–2) | 2 (1–2) | 1 (1–1) | <0.01 |
Leukopenia (cu/mm3) * | 34 (11) | 25 (30) | 8 (13) | 1 | <0.01 |
Neutropenia* | 27 (9) | 20 (24) | 7 (11) | 0 | <0.01 |
Thrombocytopenia * | 50 (16) | 42 (50) | 6 (10) | 2 | <0.01 |
Peripheral smear s/o sepsis * | 87 (28) | 65 (77) | 18 (30) | 4 | <0.01 |
CRP ( > 10 mg/dl)* | 134 (44) | 78 (93) | 54 (90) | 2 (1) | <0.01 |
Culture positive sepsis * | 59 (19) | 59 (70) | 0 | 0 | <0.01 |
CRP# | 6 (6–53) | 75.1 (30.85–100) | 39.9 (18.37–70.97) | 6.0 (6–6) | <0.01 |
