Table 2 Association between the microstructure of parapapillary atrophy and ocular parameters in highly myopic eyes.

Variables	PPA_+BM width			PPA_−BM width
Variables	Coefficients^*	P value^*	P value^†	Coefficients^*	P value^*	P value^†
Axial length (mm)	0.211	0.026	—	0.214	0.044	—
Central corneal thickness (μm)	−0.058	0.590	0.638	−0.166	0.121	0.134
Corneal curvature (D)	−0.060	0.607	0.619	0.067	0.563	0.506
IOP (mmHg)	0.068	0.536	0.475	0.071	0.519	0.456
BMO area (mm²)	0.227	0.082	0.107	0.448	<0.001	<0.001
LC thickness (μm)	−0.411	<0.001	<0.001	−0.115	0.282	0.283
Anterior laminar depth (μm)	0.312	0.002	0.002	0.155	0.147	0.197
FoBMO angle (°)	0.248	0.012	0.031	0.172	0.107	0.205
Macular BM length (μm)	0.352	0.001	<0.001	−0.040	0.708	0.848
Subfoveal CT (μm)	−0.345	0.001	0.009	−0.330	0.001	0.005
Peripapillary CT (μm)
Global	−0.176	0.101	0.189	−0.240	0.018	0.042
Temporal−superior	−0.192	0.074	0.121	−0.179	0.080	0.133
Temporal	−0.331	0.002	0.005	−0.342	0.001	0.004
Temporal-inferior	−0.189	0.078	0.090	−0.286	0.007	0.021
Nasal-inferior	−0.065	0.546	0.798	−0.127	0.240	0.407
Nasal	−0.004	0.968	0.784	−0.176	0.101	0.176
Nasal-superior	−0.112	0.300	0.370	−0.129	0.233	0.294

PPA_+BM = β-parapapillary atrophy with Bruch’s membrane; PPA_−BM = β-parapapillary atrophy without Bruch’s membrane; D = diopters; IOP = intraocular pressure; BMO = Bruch’s membrane opening; LC = lamina cribrosa; FoBMO angle = angle of fovea-to-BMO-center axis relative to the horizontal axis of the image frame; BM = Bruch’s membrane; CT = choroidal thickness.
Values with statistical significance are shown in boldface.
^*Standardized regression coefficient and P value adjusted for age and sex.
^†P value adjusted for age, sex, and axial length.
All P values were adjusted with Benjamini-Hochberg procedure.

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