Table 3 Differences according to the presence or absence of HER2 expression in differentiated-type EGC.

From: HER2 as a potential biomarker of lymph node metastasis in undifferentiated early gastric cancer

 

Total (n = 206)

Negative (n = 177)

Positive (n = 29)

p-value

Age

   

0.633

<60

72 (35.0%)

63 (35.6%)

9 (31.0%)

 

≥60

134 (65.0%)

114 (64.4%)

20 (69.0%)

 

Sex

   

0.486

M

168 (81.6%)

143 (80.8%)

25 (86.2%)

 

F

38 (18.4%)

34 (19.2%)

4 (13.8%)

 

Tumour size

   

0.158

≤20

66 (32.0%)

60 (33.9%)

6 (20.7%)

 

>20

140 (68.0%)

117 (66.1%)

23 (79.3%)

 

Vertical location

   

0.145

UT/MT

102 (49.5%)

84 (47.5%)

18 (62.1%)

 

LT

104 (50.5%)

93 (52.5%)

11 (37.9%)

 

Gross type

   

0.615

E

56 (27.2%)

47 (26.6%)

9 (31.0%)

 

F/D

150 (72.8%)

130 (73.4%)

20 (69.0%)

 

Depth of invasion

   

0.219

SM

99 (48.1%)

82 (46.3%)

17 (58.6%)

 

M

107 (51.9%)

95 (53.7%)

12 (41.4%)

 

LVI

   

0.199

No

167 (81.1%)

146 (82.5%)

21 (72.4%)

 

Yes

39 (18.9%)

31 (17.5%)

8 (27.6%)

 

Node metastasis

   

>0.99

No

184 (89.3%)

158 (89.3%)

26 (89.7%)

 

Yes

22 (10.7%)

19 (10.7%)

3 (10.3%)

 
  1. EGC, early gastric cancer; SMEGC, synchronous multiple EGC; UT, upper third; MT, mid third; LT, low third; AW, anterior wall; GC, great curvature; PW, posterior wall; LC, lesser curvature; LVI, lymphovascular invasion; VL, vertical location; HL, horizontal location.