Figure 4 | Scientific Reports

Figure 4

From: Gut microbiota manipulation during the prepubertal period shapes behavioral abnormalities in a mouse neurodevelopmental disorder model

Figure 4

Effect of prepubertal antibiotic administration on MIA-induced dysbiosis of the gut microbiota. Juvenile (P28) mice born to influenza virus-infected (MIA) mothers, or mock mothers, received a single dose of antibiotic, or vehicle, via oral gavage at P28. Cecal samples were collected from adult mice and analyzed by linear discriminant analysis effect size (LEfSe). Data are presented in a histogram with Linear Discriminant Analysis (LDA) between groups (n = 9 – 13). (A) mock (juvenile vehicle) vs. MIA (juvenile vehicle). (B) mock (juvenile vehicle) vs. mock (juvenile antibiotic). (C) mock (juvenile vehicle) vs. MIA (juvenile antibiotic). (D) MIA (juvenile vehicle) vs. MIA (juvenile antibiotic).

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