Table 1 Top 20 differentially expressed genes between WT and AGAT−/− mice in heart tissue. False-Discovery-Rate ≤ 0.05. Abbreviations: FC, fold change.

From: Analysis of L-arginine:glycine amidinotransferase-, creatine- and homoarginine-dependent gene regulation in the murine heart

Gene

Gene name

P Value

FC

Scn4a

sodium channel, voltage-gated, type IV, alpha

3.02 × 10−13

−3.22

Scn4b

sodium channel, type IV, beta

1.47 × 10−12

−3.74

Tmod4

tropomodulin 4

8.93 × 10−11

−1.76

Tmem150c

transmembrane protein 150 C

9.97 × 10−11

−2.96

Fah

fumarylacetoacetate hydrolase

1.08 × 10−10

−2.36

Agat

L-arginine:glycine amidinotransferase

1.18 × 10−10

−2.19

Lgi1

leucine-rich repeat LGI family, member 1

2.07 × 10−10

−3.10

Lad1

ladinin

2.63 × 10−10

2.17

Stom

stomatin

1.12 × 10−9

−1.41

Zfp106

zinc finger protein 106

1.31 × 10−9

1.49

Egf

epidermal growth factor

6.62 × 10−9

−1.55

Ndrg4

N-myc downstream regulated gene 4

9.12 × 10−9

1.44

Vwa8

von Willebrand factor A domain containing 8

1.20 × 10−8

−1.35

Ano5

anoctamin 5

1.78 × 10−8

−2.27

Slc16a7

solute carrier family 16 (monocarboxylic acid transporters), member 7

1.97 × 10−8

1.70

Ivd

isovaleryl coenzyme A dehydrogenase

2.54 × 10−8

−1.41

Hn1

hematological and neurological expressed sequence 1

2.60 × 10−8

1.41

Nr0b2

nuclear receptor subfamily 0, group B, member 2

3.93 × 10−8

1.47

Slc22a3

solute carrier family 22 (organic cation transporter), member 3

3.99 × 10−8

−1.66

Acsm5

acyl-CoA synthetase medium-chain family member 5

4.32 × 10−8

−1.88