Figure 3
From: Formation of distinct prion protein amyloid fibrils under identical experimental conditions
Dissociation assay of HI, MI, and LI fibrils and comparison of their secondary structures. (A) Normalized ThT fluorescence intensity values at different GuHCl concentrations, where the grey dotted line represents 50% of normalized fluorescence intensity and coloured lines correspond to each sample’s GuHCl concentration at which the 50% intensity value is reached. (B) FTIR spectra of fibril samples and second order derivative spectra (C), where grey dotted lines show wavenumbers at which the differences between spectra can be observed.
